High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases
نویسندگان
چکیده
منابع مشابه
Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral
RalGDS is one of the Ras effectors and functions as a guanine nucleotide exchange factor for the small G-protein, Ral, which regulates membrane trafficking and cytoskeletal remodeling. The translocation of RalGDS from the cytoplasm to the plasma membrane is required for Ral activation. In this study, to understand the mechanism of Ras-Ral signaling we performed a single-molecule fluorescence an...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2020
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.202006125